Autologous platelet-rich plasma or PRP has attracted attention in various medical fields recently, including orthopedic, plastic surgery and dermatology for its wound healing ability. Various growth factors, including platelet-derived growth factor (PDGF), transforming growth factor (TGF), vascular endothelial growth factor (VEGF), and insulin-like growth factor (IGF), are secreted from the α-granules of concentrated platelets. Due to the presence of high concentrations of these growth factors, PRP has been used in a wide variety of surgical procedures and clinical treatments, including skin rejuvenation and hair loss treatment.
Since PRP secretes various growth factors with roles in skin regeneration, PRP may induce collagen synthesis and other matrix components by stimulating the activation of fibroblasts, thus, rejuvenating the skin. Studies have shown that PRP stimulates dermal fibroblast proliferation, and thus can promote the remodeling of aged and photoaged skin.
Cosmetic Application of PRP (Platelet-rich Plasma)
Hair Loss Treatment
I recommend consulting with your plastic surgeon if you’re interested in PRP. PRP in combination with fat transfer for facial rejuvenation has been shown to have longer lasting results.
Emmanuel De La Cruz MD, PLLC
Plastic Surgeon, Houston | The Woodlands Texas
Kim et al. Can Platelet-rich plasma be used for skin rejuvenation? Evaluation of effects of Platelet-rich plasma on human dermal fibroblast. Ann Dermatol. 2011 Nov; 23(4): 424–431.
Published online 2011 Nov 3. doi: 10.5021/ad.2011.23.4.424